“L-arginine is currently being included in certain toothpaste formulations as it is thought to protect against dentine hypersensitivity. Our work shows that the same concentrations of L-arginine potentially can control dental plaque, and so may be beneficial in protecting against gum disease.

“There is no doubt protection against gum disease would be the major potential benefit. L-arginine is cheap and easy to add to toothpaste or mouthwash. At present, around 10-15% of adults in the Western world have advanced gum disease which can lead to loose teeth and even tooth loss. Therefore, there is a clear need for better methods to control dental plaque.”

Dental biofilms cause the formation of dental cavities, gingivitis and periodontal disease. Surveys indicate that 31% of adults in the UK have active dental cavities; and 45% have moderate or severe periodontal disease.